Hi. My name is Joel Rabasco, Head of Product at BOYDSense. Great to be here with you. Today, we’re gonna give you a live demo of the g-sense Breath Meter. But first, a little bit about BOYDSense. BOYDSense is a medtech data platform company focused on the management and monitoring of chronic conditions such as diabetes. We do this by measuring Volatile Organic Compounds, or VOCs, in exhaled breath. Our first device, the g-sense Breath Meter, can derive blood glucose values by breathing into a small handheld device. This noninvasive technology will profoundly transform the lives of everyone living with diabetes. So today, we’re gonna show you a model of our commercial device which is under development and we’re gonna give you a live, hands-on demo of the g-sense prototype. But first, let’s spend a few moments looking at the current methods used to test blood glucose. That will give you a good comparison for the seamless user experience that the g-sense Breath Meter provides. The most common way to measure blood glucose is using a BGM, or blood glucose meter. That requires a finger stick to draw blood for the sample to be used for the calculation. So, if you have diabetes, you most likely carry around a kit that looks something like this. It has multiple pieces and requires multiple steps to get a reading, so I’m not gonna demo this device, but I am gonna show you the steps involved to take your blood glucose measurement using this technology. So the first thing I need to do is I need to clean my finger with an alcohol wipe to make sure that it’s sanitized. The next thing that I do is I have to take one of these test strips and insert it into the blood glucose meter. Now, these test strips cost anywhere from 25 cents to 50 cents or even more per test strip. Now, if I’m testing my blood glucose once a day, especially if I’m testing it multiple times a day, that gets to be really expensive. So the next thing I have to do, and this is the hard part, is I have to pierce the skin of my finger with this lancet device… and it kinda stings, I don’t like it. So when I get a drop of blood, I put the blood onto the test strip that has been inserted into the meter and while I’m waiting for a reading, I have to clean my finger of the blood using this tissue here. So all in all, not the greatest user experience. It’s expensive because I have to use a test strip every time I want to get my blood glucose reading; it’s time-consuming because there’s a lot of pieces and a lot of steps; and most importantly, it’s painful. I don’t like to stick my finger. Now, the alternative to a BGM is a CGM, or continuous glucose monitor. I have a patch right here as an example. These devices, while an important element for some people with Type 1 diabetes, are far out of reach for the vast population of people that need to test their blood sugar. They are very expensive and they’re invasive in their own way. A filament has to sit under the skin, which can become very uncomfortable. The back of the patch has an adhesive, which can lead to skin irritation. It’s a little bit bulky, and so I risk having it knocked off my arm or my abdomen. Now, losing one of these patches or having it damaged requires that I replace it, and that gets to be really expensive. But most importantly, it has to be worn 24 hours a day, seven days a week, and a lot of people don’t like that. So the good news is, BOYDSense is reducing all of these barriers. So let’s see how we’re doing that. Let me show you the model of our commercial device that’s currently under development. You can see that it’s pretty small, it fits easily in my hand, and I can carry it around in my pocket. It has a lid that covers the mouthpiece, which can be removed or replaced if necessary. It has a Bluetooth or BLE radio inside as well as a cellular wireless modem that allows me to transmit data from the device to a smartphone or up into the cloud where it can be downloaded to healthcare application endpoints for clinical use. The battery lasts about 24 hours, which gives me about 12 measurements per day before I need to recharge it. But most importantly, there are no consumables, which means I don’t need to pay every time I test my blood glucose, which is very important. So let’s look at the prototype device, which I have right here. You can see it’s a little bigger, but it’s still small, very portable, and fits nicely into my hand. It’s a little bit bigger because it’s under development and we need to get inside of it to monitor the electronics and to swap out the sensor arrays. We’re currently in development to miniaturize this into this final form factor package. So in addition to the meter, we have a g-sense smartphone app; I have it loaded on my Samsung smartphone right here, you can see the homepage. So this allows me to see the readings on the device and compare them to historical readings from prior measurements. It also allows me to draw correlations between exercise, diet, medication adherence, medication, etcetera. So let’s start with the demo. It’s pretty simple and it goes by pretty fast. The first thing that I do is I start my smartphone app, and then I press the Start button on the meter. [ meter beeps ] Now, the g-sense has indicated that it’s ready for me [meter beeps ] to provide a breath sample. So what I’m gonna go is I’m gonna inhale, hold my breath for a second, and then exhale into the device. Watch this. [ exhales ] So you see the device can detect when my breath – when I’ve finished providing a breath sample. So what’s happening is my exhaled breath is being transferred from the collection chamber to the sensor chamber, where the sensors take hundreds of measurements a second. Those measurements are then fed into our proprietary algorithm where blood glucose is calculated in milligrams per deciliter (mg/dL). That value will then be sent to my smartphone, where I can see it and compare it to other readings. So we can see on my app, and the g-sense Meter has indicated to me as well that the reading is ready, and I look on my I look on my app and it shows me that my reading is 91 mg/dL, which makes sense because it’s still the morning here, I haven’t had breakfast, so my body is in a fasting state. So that’s it! Super easy, very fast, and no consumables. We’ve reduced the barriers of pain, breathing is painless, of cost, because there’s no consumables or reagents needed to test my blood sugar, and it’s really fast to do. Not a lot of steps and no pieces except for the g-sense Breath Meter. So that concludes the demo. I think you’ll agree that the g-sense provides a far superior user experience and this will lead to better engagement for people that are measuring their blood glucose. Better engagement will lead to better health outcomes in turn, which is great for everyone. If you have any inquiries, please email us at [email protected] Thank you very much, and I’ll see you next time.